7/31/2014

Call For Papers-Special Issue on Malnutrition

Call For Papers-Special Issue on Malnutrition

by SCIRP posted on AUGUST 1, 2014 [EDIT]
Bookmark and Share
Food and Nutrition Sciences
FOOD AND NUTRITION SCIENCES
This special issue on “Malnutrition” will be focusing on the latest development in food and nutrition sciences. Malnutrition, caused by an improper or insufficient diet, includes two aspects of nutritional deficiencies or lack and over nutrition. The WHO has reported hunger and related malnutrition as the greatest threat to the world’s public health. The goal of this special issue is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in this area of malnutrition.
In this special issue, we invite front-line researchers and authors to submit original research and review articles that explore malnutrition. In this special issue, potential topics include, but are not limited to:
      •  Pathogeny: fed improperly, poor eating habits, and disease factors
      •  Clinical manifestation: emaciation and edema
      •  Diagnosis and therapy of malnutrition
      •  Dietary practices
      •  Major causes of malnutrition
      •  Food security
Authors should read over the journal’s Authors’ Guidelines carefully before submission. Prospective authors should submit an electronic copy of their complete manuscript through the journal’s Paper Submission System.
 Please kindly note that the “Special Issue” under your manuscript title should be specified and the research field “Special Issue - Malnutrition” should be selected during your submission.
Also please note the following timetable:
Submission Deadline
August 5th, 2014
Publication Date
October 2014
Guest Editor:
For further questions or inquiries
Please contact Editorial Assistant at
fns@scirp.org
Posted by at No comments:

Amelioration of Diabetes Mellitus Type II after Sleeve Gastrectomy—Data on Nationwide Survey on Quality Assurance in Bariatric Surgery in Germany


Introduction: Sleeve Gastrectomy (SG) is becoming more popular due to its weight reducing effect and promising anti-diabetic efficacy. However, long term results are still lacking. Methods: The study focuses on anti-diabetic efficacy of SG through retrospective analysis of data for patients who underwent SG in Germany from 2005 to 2011. Anti-diabetic efficacy was assessed at 1, 2 and up to 4 years after surgery.Results: 5400 morbidly obese patients underwent SG. Of these 5400 patients 13.2% (n = 712) were insulin treated (IT) and 21.6% (n = 1165) were non-insulin treated (NIT). Total follow-up was accomplished in 41.24% of patients. Percentage of remission and improvement (RI) at 1 year was 83.8% (80.2% for insulin treated (IT) vs. 85.1% for non-insulin treated (NIT)). RI% at 2 years dropped to 77.6% (76.9% for IT vs. 77.9% for NIT patients). With late follow up (up to 4 years), RI% was 65.9% (58.8% for IT vs. 66.7% for NIT patients). Difference between IT and NIT patients was insignificant. Conclusion: SG shows promising ant-diabetic efficacy at 1 year, 2 years and up to 4 years after surgery. This efficacy gradually drops with prolonged time interval after surgery and seems to be insignificantly higher among NIT vs. IT patients.

http://www.scirp.org/journal/PaperInformation.aspx?PaperID=39413
Posted by at No comments:

7/30/2014

Results of Sleeve Gastrectomy in Germany—Data on Nationwide Survey on Quality Assurance in Bariatric Surgery in Germany

Background: Since January 1st of 2005, the situation of bariatric surgery is being analyzed in Germany. The data is registered prospectively in cooperation with the Institute of Quality Assurance in Surgery at the Otto-von-Guericke University Magdeburg. Methods: The data is registered through an online database which includes all information for primary and revision bariatric procedures as well as yearly follow-up. Participation in the quality assurance study is optional. All certificated centers have to participate at the survey. Results: From January 2006 to December 2009, 1478 sleeve gastrectomies (SG) were performed at 45 hospitals. The number of procedures has increased from 126 in 2007 to 933 in 2009. The main complication is leakage of the staple-line. Initial leakage rate was 7% in 2007. Leakage rate dropped down to 2.3% in 2008 and 2.5% in 2009. Mean age of patients was 43.1 years and mean BMI was 52.83 kg/m2. Age and BMI were significantly higher in patients with SG than in all other patients undergoing bariatric surgery. Conclusion: SG is a common and hype bariatric procedure in Germany, but postoperative complication rate is high. Data on the long-term effect of SG on weight loss and amelioration of comorbidities need to be evaluated. More detailed analyzes are necessary to establish the position of SG in the bariatric surgery. Further studies should also include examinations on long-term complications and redo-procedure after SG.
Posted by at No comments:

The Role of Fear of Negative Evaluation in Predicting Depression and Quality of Life Four Years after Bariatric Surgery in Women

The purpose of this study was to investigate the role of fear of negative evaluation (FNE) in predicting psycho-social functioning (depression and quality of life (QOL)) as a function of amount of weight lost four years after weight loss surgery among women. Four years after gastric bypass surgery, female participants (N = 29) com-pleted measures of FNE, depression, and QOL via telephone. Height and weight (pre- and post-surgery) were obtained from medical charts and current primary care physicians. FNE was not related to depression or QOL among patients who lost less weight. However, FNE predicted greater depression and worse QOL among those who had lost more weight four years after surgery. Several potential explanations are explored. Regardless of why social concerns are related to mood and QOL for certain individuals post-surgery, psychosocial therapy that addresses life transitions after weight loss, with particular focus on concerns about interpersonal evaluation, might improve mental health outcomes for women after bariatric surgery.
Posted by at No comments:

Quality of Life (QOL) in Long-Term Survivors of Osteosarcoma

We conducted this study to analyze the quality of life using the SF-36 health questionnaire and the MSTS scores depending on surgical method and the primary site of occurrence. On the surgical method, the limb salvage had more excellent outcomes (60.9) than the amputation (46.3). The tumor prosthetic replacement had notably higher scores (62.5) than any other methods. For the correlation coefficients on the MSTS and SF-36, the Physical Function had the highest degree of correlation. Excellent functions of the extremities would lead to a good quality of life.
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=27787

Posted by at No comments:

Clinical Study on the Impact of Long-term Survival Quality in 204 Postoperative Patients with Breast Cancer by Cox Proportional Hazard Models

The aim of study was to evaluate clinical characteristics, social support and the association with the prognosis of breast cancer patients. A total of 204 participants were followed from 2003 until the end of 2008. Information about patients with breast cancer was submitted by investigators. Data were analyzed by Cox’s proportional hazard model. The clinical staging of breast cancer we used was the TNM classification. A "T" score is based upon the size and/or extent of invasion. The "N" score indicates the extent of lymph node involvement. Age at diagnose was associated with protective factors (HR=0.972; 95%CI (0.834-1.130)), T staging (HR=2.075; 95%CI (1.424-3.022)), N staging (HR=1.513; 95%CI (1.066-2.148)), were associated with risk factor. Two survival graphs of nodes with negative effects by histology and nodes with positive effects by histology was analyzed by log-rank test, there was statistically significant relationship between two survival graphs (χ2 =136.8467, p <.0001). Age at diagnoses, Clinical stage tumor and node could contribute to the development of breast cancer and disease free survival in Chinese women.

Posted by at No comments:

Numerical Study of Slip Effect of Unsteady MHD Pulsatile Flow through Porous Medium in an Artery Using Generalized Differential Quadrature Method (Comparative Study)

Author(s)    Leave a comment
ABSTRACT
The unsteady pulsatile flow of blood through porous medium in an artery has been studied under the influence of periodic body acceleration and slip condition by considering blood as incompressible Newtonian electrically conducting fluid in the presence of magnetic field. In this paper, a new technique of differential quadrature method is introduced to find numerical solution of non-linear partial differential equations such as the equation of motion of this problem “Navier-Stokes equation”. The presence of the nonlinearity in the problem leads to severe difficulties in the solution approximation. In construction of the numerical scheme “a new algorithm” a generalized differential quadrature method (GDQM) is to use for derivatives with respect to space variables of differential equations and for the time derivative applying fourth order RungeKutta Method (RKM). The GDQM changed the nonlinear partial differential equations into a system of nonlinear ordinary differential equations (ODEs). The obtained system of ODEs is solved by 4th order RKM. This combination of DQM and 4th order RKM gives a very good numerical technique for solving time dependent problems. The algorithm is coded in Matlab 7.14.0.739 and the simulations are run on a Pentium 4 CPU 900 MHz with 1 GB memory capacity. The effects of slip condition, magnetic field, porous medium, and body acceleration have been discussed. The numerical results show that the proposed method is more accurate and convergent than other numerical methods in literature. The method is illustrated and compared with the exact and analytical solutions and it is found that the proposed method gives a better accuracy and is quite easy to implement.
Posted by at No comments:

Fractured Metal Wire in the Right Ventricle, a Cause of Cardiac Tamponade

Cardiac tamponade is a surgical emergency. This case report illustrates a very peculiar situation, where the patient’s condition deteriorated rapidly after arrival to the emergency room with a diagnosis of cardiac tamponade. Patient was promptly taken to the operating room and after evacuation of the pericardial effusion, had to be placed on cardio-pulmonary bypass in order to find and treat the source of the bleeding. A wire fragment was recovered from the right ventricle. This was identified as a broken piece of a guide wire used in placing a central venous catheter several years earlier.
Posted by at No comments:

Pseudoaneurysm after abdominal myomectomy: A rare but catastrophic complication

Background: Uterine artery pseudoaneurysm is a rare diagnosis made postoperatively after pelvic surgery. The exact etiology is unknown however it is speculated to occur when an artery is lacerated and the perivascular tissue maintains persistent blood flow with the parent vessel. It can present with severe hemorrhage two to four weeks after an uncomplicated post operative course. Case: A 45 year old presented with vaginal hemorrhage and hypotension two weeks after abdominal myomectomy. Transvaginal ultrasound with doppler diagnosed pseudoaneurysm of the uterine artery. The patient was successfully treated with endovascular embolization utilizing micro coils. Conclusion: Transvaginal ultrasound is a useful technique in diagnosing pseudoaneurysms. Endovascular embolization is a minimally invasive, safe and effective way to treat this rare complication in institutions that have access to interventional radiology procedures.
Posted by at No comments:

The effect of aerobic training on endothelium-dependent vasodilatation in patients with coronary artery disease who were revascularized and young men

Aim: The aim of this study was to determine the effect of training on endothelium-dependent vasodilatation in patients with coronary artery disease (CAD) after revascularization and healthy young men. Background: Impaired endothelial function has been observed in patients with CAD and those with CAD risk factors. Studies have shown that exercise can enhance endothelial function. Methods: This experimental cross-sectional study was conducted on patients with CAD (3 months after CABG and PCI) and students of medical school in 2011. Endothelium dependent dilation of the brachial artery was determined by using high-resolution vascular ultrasonography through flow-mediated vasodilatation (FMD) after induction of ischemia, and the data were analyzed using SPSS, dependent t-test and ANCOVA. Findings: The findings showed that at baseline, FMD was reduced in revascularized patients, when compared with healthy young men, after 8 weeks, and exercise training significantly improved FMD in patients underwent training group [from 4.31 ± 1.45 (SD)% to 6.15 ± 0.773 (SD)%, p < 0.05] and substantially increased the same in healthy young men [from 9.18% ± 1.45% to 11.72% ± 1.72%, p < 0.05] However, in the control group, the FMD remained unchanged, and even after aerobic training, it did not significantly modify the brachial artery diameter in these groups. Conclusion: Our study demonstrates that endothelial dysfunction persisting in CAD patients after revascularization and aerobic training can improve endothelial function in different vascular beds in CAD patients and healthy young men. This may contribute to the benefit of regular exercise in preventing and restricting cardiovascular disease.
Posted by at No comments:

Effect of topical vasodilator on internal thoracic artery blood flow. A placebo-controlled clinical study

Objective: The internal thoracic artery (ITA) is the conduit of choice for coronary artery bypass grafting (CABG). To avoid spasm of the ITA various topical vasodilators have been suggested either intraluminally or by topical application. In order to describe the best vasodilating agent for preparation of the ITA, a randomized double-blind placebo controlled clinical work was performed in a group of CABG patients. Methods: Three hundred consecutive patients submitted for elective first time coronary artery bypass grafting were randomly subdivided into five groups. The first measurement was performed shortly after the internal thoracic artery was dissected from the chest wall and the second just prior to performing distal anastomosis to the left anterior descending coronary artery. During the time interval between the two measurements topical vasodilator has been injected into the endothoracic fascia of the ITA using the following drugs: papaverine 2 mg/ml, nitrogly-cerin 1 mg/ml, nitroprusside 0.5 mg/ml, mixed solution include sodium nitroprusside (1 mg/ml) and diltiazem (0.5 mg/ml) and normal saline 0.9%. Results: No statistically significant differences were found between the groups in respect to age, body surface area, cardiopulmonary bypass time, cross clamping time, and time interval between the two flow measurements. Mean arterial pressure at the time of the first and second internal thoracic artery flow measurements did not show statistically significant differences either within or between the groups. In all five groups, the free flow of the internal thoracic artery increased significantly with time. However, no statistically significant differences were shown between the five groups with respect to second flow. Conclusions: We suggest that preparation of the ITA by topical vasodilators injection into the endothoracic fascia does not result in a significantly superior free flow than placebo.
Posted by at No comments:

Structural characteristics of Mulato Grass under different cutting Heights

Structural characteristics of Mulato Grass under different cutting Heights

Author: Eneas Reis Leite
Native pastures are the main sources of food for ruminants in Northeast Brazil. Considering that animal feeding represents 70% to 80% of total costs, it is justifiable to maximize the use of pastures. Their correct use allows the conversion of structural carbohydrates into proteins of high biological value at a relatively low cost.
Grasses from Brachiaria genus are the basis of animal production in the tropics, allowing extensive areas for livestock, including those being considered as marginal zones due to the low quality soils, which represent more than 40 million hectares in Brazil.
The morphogenic variables determine the structural characteristics of pastures, and the most important are the number and size of leaves and tiller density. These structural characteristics present high correlation with the intake plant species the animals will select, so that they  constitute important factors for evaluation of pasture quality of grasses of economic interest..
The knowledge of morphological and physiological features of forage grasses represent the starting to the basic understanding of plant responses to cut or grazing. In Eneas Leite´s research from Department of Animal Science at Acacaú Valley University, in Brazil, published  inAmerican Journal of Plant Sciences 2014, vol. 5, deeper study on Mulato Grass (Brachiaria hibrida) have evaluated the effects of different heights of cuts, in four periods of the year, on structural characteristics of this forage species.
In general, it was concluded that the use of cutting at 10 cm causes a reduction in the total dry matter production of Mulato Grass. Cutting heights between 20 and 30 cm contributes positively to increasing the total number of leaves, the number of green leaves, the average size of the leaf blade and the total dry matter production. Cuttings near 40 cm are not recommended because they are responsible for the decrease in leaf/stem ratio and for the increasing in stem fractions and dry matter content, thus affecting the structure of the canopy. Further studies indicate the need of studying the structural characteristics together with the qualitative characteristics for a better understanding of this forage management.

source:

Journal： American Journal of Plant Sciences
DOI: 10.4236/ajps.2014.55077 (PDF)
Paper Id: 43665 (metadata)
Posted by at No comments:

7/28/2014

Increasing oil production using high power ultrasound

Author ：Anna Abramova
Today the average oil recovery in the world is less than 40%. This means that 60% of the reserves stays in the formation and can’t be extracted using the existing technologies. Thus, development of new technologies for enhanced oil recovery is a very urgent task.
However, there are more and more concerns about the environmental aspect of oil recovery. The technologies which enable the producers to extract additional oil are often energy-intensive, labor-intensive and not environmentally safe.
The use of high power ultrasound in oil wells has been explored over the last years. Based on years of research e innovative ultrasonic technology has been developed. This technology is totally safe as it doesn’t involve dangerous chemicals and affects only the wellbore perforation zone of the well, which is often polluted by resins, asphaltenes and paraffin.
This technology has been tested on more than 100 wells in Siberia and the Volga region and showed very good results. One operation lasts about 20 hours and increases the oil production in average by about 30 bbl/day in Western Siberia and by about 70 bbl/day in the Volga region. The effect of the treatment last from 3 month to 2 years depending on the formation.
Thus, a new promising technology for enhanced oil recovery has been developed. The main advantages of the ultrasonic EOR technology are: low energy consumption, the possibility to treat the reservoir selective, no harm to the well and its casing, no harm to the environment and to people.

source:

Journal： Engineering
DOI: 10.4236/eng.2014.64021 (PDF)
Paper Id: 43803 (metadata)
See also: Comments to Paper
Posted by at No comments:

7/27/2014

Effect of Environmental Taxes as Correcting Negative Externalities Caused by Water Pollution Applied to the Agro-Food Industry

Market failure involving pollution from wastewater discharges industrials, is corrected with the establishment of environmental taxes. Heterogeneity in the design of these taxes, with a different tax base for each EU member country, affects both the pollution parameters considered and their weight in the calculation of the tax payable. This paper presents a study on the variety of this tax in Belgium, Italy and Spain. Finally, we discuss the possibility of the same as correcting market failure.
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=33215
Posted by at No comments:

Story of a Little Right Ventricular Pseudoaneurysm

Cardiac trauma caused by Swann-Ganz catheter may very rarely cause cardiac perforation, tamponade and right ventricular pseudoaneurysm. In contrast to left ventricular equivalants, pseudoaneurysms of the RV have a weak tendency to rupture. Its impact on patient outcomes should be assesed very carefully depending on its size, filling rate/capacity. It is possible not to operate the patient and follow progression of RV pseudoaneurysm by clinical and echocardiographic findings. This case is a good sample for it and describes the lifespan of a small RV pseudoaneurysm. It is not only the unique right ventricle pseudoaneurysm due to cardiac trauma caused by Swann Ganz catheter, but medically treated case without surgery and recovered completely.

Posted by at No comments:

7/21/2014

Effect of Slip Velocity on Blood Flow through a Catheterized Artery

A mathematical model for pulsatile flow of blood in a catheterized artery in presence of an axisymmetric stenosis with a velocity slip at the constricted wall is proposed. The expressions for the flow characteristics, velocity profiles, the flow resistance, the wall shear stress, the effective viscosity are obtained in the present analysis. The effects of slip velocity on the blood flow characteristics are shown graphically and discussed briefly.
Posted by at No comments:

Study the effect of exercise on systolic pulmonary artery pressure in healthy subjects

Introduction: As no data is available concerning the cut-off value defining abnormal pulmonary artery systolic pressure (PASP) response in subjects of various ages, the aim of this study is to assess physiological PASP response to exercise in healthy individuals of various ages. Material and methods: One hundred and twenty three healthy volunteers, aged 30 to 70 years, underwent Doppler echocardiographic measurements at rest and after treadmill exercise test. Pulmonary artery systolic pressure was estimated at rest, and immediately after peak exercise using Bernoulli formula (four times tricuspid valve regurgitation velocity squared adding an estimated right atrial pressure). Results: Lower and upper limits of PASP during rest was 7 and 28 mmHg and after peak exercise was 14 and 48 mmHg respectively. After exercise, PASP increased from rest (14 ± 4 mmHg) to peak (25 ± 7 mmHg). Pulmonary artery systolic pressure during rest and peak exercise, increased with age, but has no correlation with body mass index or gender. Conclusion: Pulmonary artery systolic pressure at peak exercise can frequently reach values ≥ 30 mmHg in healthy individuals with good exercise capacity, especially in elderly individuals, which goes beyond pathologic definitions of pulmonary hypertension.
Posted by at No comments:

The association of adenosine deaminase with coronary artery disease: Effect of gender and diabetes

An association between ADA1 and Coronary Artery Disease (CAD) has been observed in Polish and in Italian populations but in Italian population the association was present in males only. In order to enlighten these differences we have carried out a collaborative study in the two populations. In Italy 215 subjects admitted to the Hospital for CAD, 275 subjects with Type 2 Diabetes (T2D) without CAD and 398 healthy new-borns were studied. In Poland 173 subjects with CAD and 200 healthy newborns were studied. Written informed consent was obtained from all subjects or from their mothers to participate to the study that was approved by the I.R.B. ADA1 polymorphism was determined by DNA analysis. Three way contingency table analysis was performed by a log linear model. The association between CAD and ADA1 is present in non diabetic male subjects only: OR = 0.195, p = 0.007 in the Italian population and OR = 0.163, p = 0.004 in the Polish population. The data suggest a significant role of immunological mechanisms in the pathogenesis of CAD without diabetes. Gender differences in immune diseases could explain the lack of association in females.
Posted by at No comments:

Effect of tapered angles in an artery on distribution of blood flow pressure with gravity considered

The tapered angles of an artery significantly influence the local hemodynamics. However, as gravity is considered, little is known about the effect of tapered angles on the hemodynamics. In this study, we explored whether the effect of tapered angles on the distribution of blood flow pressure (DBFP) differed with gravity considered or not. Numerical simulations of the DBFP in a single vessel were performed based on such tapered angles as 0°, 0.5° and 1°. In the model used for simulation, gravity was introduced as a body force. We obtained the following simulations: i) The larger the tapered angles were, the better distributed the blood flow pressure; ii) The tapered effect was an important factor leading to nonlinearity in blood flow pressure; iii) Gravity affected DBFP coupling with the tapered angles, yet independently influenced the dimension of the DBFP. At the same time, the effective intensity of gravity decreased with the increase of tapered angles.
Posted by at No comments:

Successful coil embolization with a basic technique for ruptured posterior tibial artery in a patient with Ehlers-Danlos syndrome type IV: A case report

The surgical management of vascular complication with Ehlers-Danlos Syndrome type IV (EDS-IV) is extremely challenging because of its tissue or organ fragility including arteries. Less traumatic maneuvers and devices have been recommended to perform the endovascular treatment for the vascular lesion of EDS-IV, although the endovascular procedure is less invasive than surgical intervention. We report a 23-year-old man with EDS-IV suffered from left posterior tibial arterial rupture. We performed internal trapping of the ruptured segment using detachable coils with a standard technique via the contralateral femoral artery puncture. The patient was discharged without any complication associated with the endovascular procedure. Embolization by a basic technique, performed with greatest care, is a safe and useful treatment option which we radiologists should try for managing EDS-IV patients.
Posted by at No comments:

Effect of gestational protein restriction on left ventricle hypertrophy and heart angiotensin II signaling pathway in adult offspring rats

Maternal protein restriction may be a risk factor for cardiovascular disorders in adulthood. The RAS (renin-angiotensin-system) plays a pivotal role in cardiac remodeling. Components of the RAS, including angiotensin II (AngII) and its receptors type 1 (AT1R) and 2 (AT2R) are expressed in the heart. This study investigates whether gestational protein restriction alters the expression and localization of AT1R and AT2R and RAS signaling pathway proteins in parallel with left ventricle hypertrophy and systemic hypertension in male offspring. Dams were kept on normal (NP, 17% protein) or low (LP, 6% protein) protein diet during pregnancy. Systolic blood pressure (SBP) of male offspring was measured from the 8th to 16th week and left ventricles of 16-wk-old rats were processed for histology, morphometric, immunoblotting and immunohistochemistry. LP offspring showed a significant reduction in birth body weight and SBP increased significantly from the 8th week. Left ventricle mass and cardiomyocytes area were also significantly higher in LP animals. Widespread perivascular fibrosis was not detected in the heart tissue. Analysis by immunoblotting and immunohistochemistry demonstrated a significant enhance in cardiomyocyte expression of AT1R and ERK1 in LP offspring. Expression of PI3K in LP was significantly reduced in cardiomyocytes and in the intramural coronary wall, while AT2R expression was unchanged in the NP group. We also found reduced LP expression of JAK2 and STAT3. In conclusion, our data also suggest that changes in the RAS may play a role in the ventricular growth through upregulation of the AT1-mediated ERK1/2 response, despite unchanged AT2R expression.
Posted by at No comments:

Levosimendan usage in patients with left ventricle dysfunction in coronary artery bypass graft surgery

Introduction: In this study we explicated early results of patients (the patients in whom levosimendan was used) who underwent coronary artery bypass graft surgery with ejection fraction 35% or less. We compared this group with the patients in whom levo-simendan was not used. Material and Methods: 97 patients who have 35% ejection fraction or less taken to isolated coronary artery bypass surgery between January 2009 and December 2011 in our clinic are chosen for this study retrospectively. We compared the patients in whom levosimendan was used with the patients in whom levosimendan was not used. Levo- simendan (Simdax, Abbott) has been used according to surgeon’s decision in patients. Results: The mean age of group 1 was 62.3 ± 7.6, and the mean age of group 2 was 59.3 ± 10.5 (p > 0.05). It was detected that the average ejection fraction was less in group 1 (p < 0.05). There were no statistically significant difference between the two groups in terms of demand for inotropics, demand for intraaortic balloon pump, revision (because of bleeding), atrial fibrillation, discharging intervals, intensive care unit time, cross clamp and cardiopulmonary bypass time (p > 0.05). It was found that need for blood transfusion were less in group 1 than group 2 (p < 0.05). There were no statistically significant difference between the two groups in terms of mortality (p > 0.05). Conclusion: We consider levosimendan reduces need for blood transfusion in coronary artery bypass graft surgery. This results may change with increasing number of patients so we consider that multicenter larger study is needed.
Posted by at No comments:

Doppler measurements in fetal descending aorta and umbilical artery can predict borderline oxygenation in pre-eclampsia and HELLP syndrome

Objective: To determine diagnostic utility of Doppler measurements in fetal descending aorta and umbilical arteries in predicting intrauterine growth retarded (IUGR) fetuses at risk in pregnancies complicated by preeclampsia and/or HELLP syndrome. Methods: Doppler measurements were taken in fetal descending aorta and umbilical arteries of 53 patients with pre-eclampsia, 10 of whom had HELLP syndrome using fetometry (ACUSON 128XP/10, 3.5 MHz probe). These values were compared with those of 44 appropriate-for-gestational age singleton pregnancies (AGA). Doppler Indices (Resistance Index (RI), Systolic/Diastolic (S/D) ratio) and end-diastolic flows were related to fetal heart rate (FHR) during contraction stress test, to cord blood parameters (pH, Base Excess) and to Apgar Scores. Results: In contrast to AGA fetuses, IUGR fetuses had decreased end-diastolic flow and an increase of Doppler Indices significantly earlier in the descending aorta (p < 0.05), compared to umbilical artery. Increased RI’s, S/D ratios and a decrease of end-diastolic flow in fetal aorta were significantly correlated to frequency of FHR decelerations during contraction stress tests, pH, Base Excess (p < 0.01) and Apgar Scores in IUGR fetuses. Conclusion: A decrease in end-diastolic flow paralleled with an increase in Doppler indices in fetal descending aorta reflect oxygen deprivation in IUGR fetuses during pre-eclamptic pregnancies with or without HELLP syndrome. While ductus venosus and umbilical artery are more frequently used nowadays to determine fetal oxygen deprivation, Doppler measurements in fetal descending aorta provide additional information for early detection of fetuses at risk for IUGR in pregnancies complicated with pre-eclampsia and/or HELLP syndrome
Posted by at No comments:

Sex Difference in Lactate Production by Adipocytes from Lean Humans

Sex Difference in Lactate Production by Adipocytes from Lean Humans

The obesity is the focus of very important scientific researches due to high incidences of this disease in our society. Understanding the metabolism of adipocytes can help in comprehension of this disease. In this work Sex Difference in Lactate Production by Adipocytes from Lean Humans, we investigated the gender differences in lactate production by adipocytes isolated from lean human visceral adipose tissues. We show that adipocytes isolated from lean women produced as much lactate as glycerol, whereas adipocytes isolated from lean men produced three times more glycerol than lactate. The studies about gender metabolic differences in isolated adipocytes from lean humans could be useful for human physiology comprehension in lean and obese humans.

source:

Posted by at No comments:

7/16/2014

Long-term clinical efficacy of ostial stenting to the left anterior descending artery with deep caudal projection

Purpose: Overlapping and foreshortening on conventional coronary angiography is one reason why the presence of ostial lesions in the left anterior descending artery (LAD) is an independent predictor of insegment restenosis. Our previous study using 3-dimensional reconstruction coronary angiography demonstrated the superiority of a deeper caudal projection in clearly showing the ostium of the LAD compared to the standard right or left anterior oblique caudal view. Therefore, the aim of this study was to determine the short-and long-term efficacy of the ostial stenting technique using a deep caudal projection angle. Methods: A total of 30 consecutive patients who underwent stent deployment to treat LAD lesions positioned at the proximal edge of the stent in the ostium with a deep caudal projection were analyzed retrospectively. Results: The projection of right anterior oblique caudal 40° was used in 26 patients and that of left anterior oblique caudal 40° was used in four patients. Intravascular ultrasound examinations showed complete coverage of the ostium by the stent in 29 patients. In one patient, the stent did not cover the ostium. The mean protrusion of the stent over the ostium was 0.66 ± 0.85 mm. During the follow-up period (1203.5 [982-1329] days), the rate of target lesion failure was 16.7%, and there were no cases with in-stent restenosis of the main branch in which a drug-eluting stent covering the ostium of the LAD was successfully deployed. Conclusions: Focal stent placement using a deep caudal projection is a feasible and effective therapeutic strategy for treating ostial lesions in the LAD.


http://www.scirp.org/journal/PaperInformation.aspx?PaperID=39688
Posted by at No comments:

Percutaneous Embolization of a Hepatic Artery Pseudoaneurysm under Combined Angiographic and Fluoroscopic Guidance


Hepatic artery pseudoaneurysm is a rare complication of liver directed procedures. Several strategies for treatment of pseudoaneurysms have been described. We describe a challenging case in which a small bleeding hepatic artery pseudoaneurysm is complicated by a proximal hepatic arterial occlusion, preventing transcatheter access. The aneurysm was too small to be seen on ultrasound. Using combined angiographic and fluoroscopic guidance, however, the aneurysm was triangulated and successfully treated with percutaneous direct thrombin injection. Combined angiography and fluoroscopy guided percutaneous thrombin injection of intrahepatic pseudoaneurysms can be a valuable treatment approach, particularly when other methods are not feasible or have failed.


http://www.scirp.org/journal/PaperInformation.aspx?PaperID=46910
Posted by at No comments:

Endovascular Repair of an Infected Broken Pseudoaneurysm of the Extracranial Internal Carotid Artery

The formation of pseudoaneurysms after carotid endarterectomy is extremely rare. Treating those pseudoaneuryms is necessary because of the risks for continued expansion, rupture and distal embolism. Traditional surgical repair of carotid artery pseudoaneurysms is associated with a high morbidity and mortality. An endovascular approach to these infected pseudoaneurysms limits the risk for operative damage to surrounding structures and potential blood loss.
Posted by at No comments:
Subscribe to: Posts (Atom)